Product photos are for illustration. Brands update their packaging and formulas without notice, so the item you receive may look different from the photo.

Uriage Dépiderm Anti-Spot Serum Radiance Booster

Brand: Uriage

Type: Face Serum

Regular price $63.99
Purchase options

Auto-renews, skip or cancel anytime.

Subscription policy

Authentic French pharmacy formula

Sourced in Paris, shipped from California or Paris, in its original packaging.

Free US shipping over $100*

Tracked delivery on every order.

Large or heavy orders may carry a small additional charge, shown at checkout.

Delivered in 3 to 10 business days

Ships from California or Paris, tracked all the way to your door.

Returns within 30 days

Unopened products, returned by mail.

Your skin shows post-acne marks, sun spots, or uneven tone that over-the-counter creams barely touch. Uriage Depiderm Anti-Spot Serum targets stubborn hyperpigmentation at the source with clinically tested brightening actives and soothing Uriage Thermal Water. You get corrective power plus mineral calm for reactive skin.

Key Benefits

  • Fades post-acne dark marks: targets hyperpigmentation where it forms, lightening visible spots over weeks
  • Evens skin tone: your complexion looks uniform and luminous with consistent daily use
  • Boosts radiance: dull skin regains brightness without harsh exfoliants
  • Soothes reactive skin: isotonic Uriage Thermal Water calms irritation and strengthens your barrier
  • Lightweight texture: absorbs fast, layers perfectly under moisturizer or SPF with no sticky residue

Key Ingredients

Uriage Thermal Water: naturally isotonic mineral formula that soothes sensitive skin and reinforces your barrier. Clinically tested brightening actives: work together to reduce visible dark spots and even tone over time.

Shop all Uriage products at Paris Pharmacy.

Full details

How to Use

Apply to cleansed skin every morning and evening. Dispense 2 to 3 drops onto your fingertips. Smooth over your entire face, focusing on areas with visible dark spots. Let absorb fully for one minute. Follow with your moisturizer. In the morning, always apply broad-spectrum SPF30 or higher after the serum, because brightening actives increase sun sensitivity. For stubborn pigmentation, pair with Uriage Depiderm cream at night.

Ingredients

Key Ingredients

Uriage Thermal Water: naturally isotonic mineral formula that soothes sensitive skin and reinforces your barrier. Clinically tested brightening actives: work together to reduce visible dark spots and even tone over time.

Frequently Asked Questions

Can I use this serum if I have sensitive skin?

Yes, the formula is dermatologist-tested for sensitive and reactive skin types. Uriage Thermal Water base soothes while the brightening actives work, so irritation stays minimal. Start nightly for one week, then add morning application.

How long before I see dark spots fade?

Most users notice visible lightening of post-acne marks and sun spots within 4 to 6 weeks of twice-daily use. Stubborn pigmentation may take 8 to 12 weeks. Pair with broad-spectrum SPF every morning for faster, lasting results.

Do I need to refrigerate this serum?

No, store at room temperature away from direct sunlight. The formula stays stable for 12 months after opening. Keep the cap tightly closed between uses to preserve potency.

Can I layer this under retinol at night?

Yes, apply Depiderm serum first on clean skin, wait two minutes, then follow with retinol. The soothing Uriage Thermal Water base helps buffer potential irritation. Always use SPF the next morning.

Specifications

SKU
PP3661434009754
Barcode
3661434009754
Size
30ml
Made in
France
Type
Face Serum
Brand
Uriage

Shipping and Returns

  • Free US shipping over $100*

    Tracked delivery in 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Orders below $100* ship at a flat rate shown at checkout.

    Large or heavy orders may carry a small additional charge, shown at checkout.
  • Duties paid to the US

    US orders ship DDP: duties and taxes are paid upfront, nothing to pay at delivery. International orders may be subject to local duties and taxes on delivery, charged by the carrier.

  • 30 day returns

    Unopened products in their original packaging, within 30 days of delivery. Email us and we send a prepaid return label.

Read the full shipping and returns policy

Why Paris Pharmacy

  • Authentic French pharmacy products

    Sourced from French pharmacy suppliers, in their original packaging with batch codes.

  • The French pharmacy brands

    La Roche-Posay, Avene, Vichy, Bioderma, Caudalie, NUXE and more.

  • Shipped from California or Paris

    US orders: 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Every order is tracked.

  • Questions? Ask us

    Write to contact@parispharmacy.com or use the chat.

Read our full story

Questions about this product? Chat with us

Payment and Security

  • Payment methods we accept
  • Amazon
  • American Express
  • Apple Pay
  • Bancontact
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • MB WAY
  • PayPal
  • Satispay
  • Shop Pay
  • USDC
  • Visa

Checkout is secured by Shopify over an encrypted connection, and your card details are never stored on this site. Returns are accepted within 30 days: read our shipping and returns page and our privacy policy.

Uriage Dépiderm Anti-Spot Serum Radiance Booster
Uriage Dépiderm Anti-Spot Serum Radiance Booster
Regular price $63.99

Free US shipping over $100*

Tracked, duties paid to the US. Arrives in 3 to 10 business days.

Large or heavy orders may carry a small additional charge, shown at checkout.

30 day easy returns

Return unopened products within 30 days. Damaged items replaced at no cost.

Authentic, direct from France

Real batch codes and original packaging, bought from French pharmacy brands.

As seen on Instagram

Paris Pharmacy on Instagram

Routines, unboxings and how to use, straight from our feed.

Play Reapply, every two hours
paris.pharmacy

Reapply, every two hours

Play Caudalie SPF 50 at the beach
paris.pharmacy

Caudalie SPF 50 at the beach

Play Caudalie Vinoperfect and the Instant Detox Mask
paris.pharmacy

Caudalie Vinoperfect and the Instant Detox Mask

Play Love these recs, find all these and more
paris.pharmacy

Love these recs, find all these and more

Play A French pharmacy haul, from A313 to Homeoplasmine
paris.pharmacy

A French pharmacy haul, from A313 to Homeoplasmine