Product photos are for illustration. Brands update their packaging and formulas without notice, so the item you receive may look different from the photo.

La Roche-Posay Effaclar Duo+M Blemish Moisturizer

Brand: La Roche-Posay

Type: Acne Treatment

Regular price $25.99
Purchase options

Auto-renews, skip or cancel anytime.

Subscription policy

Authentic French pharmacy formula

Sourced in Paris, shipped from California or Paris, in its original packaging.

Free US shipping over $100*

Tracked delivery on every order.

Large or heavy orders may carry a small additional charge, shown at checkout.

Delivered in 3 to 10 business days

Ships from California or Paris, tracked all the way to your door.

Returns within 30 days

Unopened products, returned by mail.

La Roche-Posay Effaclar Duo+M clears your breakouts and fades post-acne marks daily. Oily shine, clogged pores, and stubborn blemishes keep coming back for a reason. This formula targets the root cause. Your skin grows clearer and less greasy with each use.

Key Benefits

  • Fades post-acne marks: Procerad targets red and brown marks so they clear faster.
  • Controls oily shine: Phylobioma targets sebum overproduction so your pores look visibly smaller.
  • Evens skin tone: Niacinamide calms redness for a more balanced complexion.
  • Unclogs pores gently: LHA and Salicylic Acid exfoliate without stripping your skin.
  • Fights acne at the source: Targets the C. acnes type linked to excess sebum.
  • Dermatologist-tested formula: La Roche-Posay Effaclar Duo is safe for sensitive, oily, and blemish-prone skin.

Key Ingredients

Procerad: a patented complex that targets red and brown post-acne marks, helping them fade faster. Phylobioma: a microbiome-derived active that addresses the C. acnes phylotype responsible for excess sebum. Niacinamide: a vitamin B3 derivative that calms redness and helps balance an uneven skin tone. LHA and Salicylic Acid: gentle chemical exfoliants that unclog pores and smooth skin texture without irritation.

Shop all La Roche-Posay products at Paris Pharmacy.

Full details

How to Use

Apply a pea-size amount to clean, dry skin every morning and evening. Gently massage over your entire face, avoiding the eye area. For active blemishes, press a thicker layer on the spot. This targets it directly. Follow with SPF in the morning. No rinse needed.

Ingredients

Key Ingredients

Procerad: a patented complex that targets red and brown post-acne marks, helping them fade faster. Phylobioma: a microbiome-derived active that addresses the C. acnes phylotype responsible for excess sebum. Niacinamide: a vitamin B3 derivative that calms redness and helps balance an uneven skin tone. LHA and Salicylic Acid: gentle chemical exfoliants that unclog pores and smooth skin texture without irritation.

Frequently Asked Questions

How long until I see results with Effaclar Duo+M?

Most users see fewer breakouts and less oily shine within 4 weeks. This timeline applies to active breakouts. Post-acne marks fade more slowly, often 8 to 12 weeks. Consistent daily use is essential. Apply every morning and evening without skipping days. Skipping sessions extends the timeline.

Is La Roche-Posay Effaclar Duo safe during pregnancy?

This product contains LHA (a salicylic acid derivative) and salicylic acid. Salicylic acid (a BHA) is generally not recommended during pregnancy or breastfeeding. Please check with your physician before using it.

Can I use Effaclar Duo+M with a retinol serum?

Yes, but use retinol at night only and apply Effaclar Duo+M in the morning. Layering both at the same time can increase sensitivity. Separate AM and PM use reduces irritation risk. Introduce retinol slowly and watch for redness or peeling. If irritation appears, reduce retinol frequency first.

How do I use La Roche-Posay Effaclar Duo correctly?

Effaclar Duo+M works as both a daily moisturizer and a spot treatment. Apply a small amount to clean, dry skin every morning and evening. Massage gently over your full face, avoiding the eye area. For active blemishes, press a thicker layer directly on the spot.

Is La Roche-Posay Effaclar Duo discontinued?

No, Effaclar Duo is still in production. The formula has been updated over the years. The current version is Duo+M, adding microbiome technology. It ships directly from French pharmacies to the US. You can order the same formula sold in Paris today.

Specifications

SKU
PP3337875863377
Barcode
3337875863377
Made in
France
Type
Acne Treatment
Brand
La Roche-Posay

Shipping and Returns

  • Free US shipping over $100*

    Tracked delivery in 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Orders below $100* ship at a flat rate shown at checkout.

    Large or heavy orders may carry a small additional charge, shown at checkout.
  • Duties paid to the US

    US orders ship DDP: duties and taxes are paid upfront, nothing to pay at delivery. International orders may be subject to local duties and taxes on delivery, charged by the carrier.

  • 30 day returns

    Unopened products in their original packaging, within 30 days of delivery. Email us and we send a prepaid return label.

Read the full shipping and returns policy

Why Paris Pharmacy

  • Authentic French pharmacy products

    Sourced from French pharmacy suppliers, in their original packaging with batch codes.

  • The French pharmacy brands

    La Roche-Posay, Avene, Vichy, Bioderma, Caudalie, NUXE and more.

  • Shipped from California or Paris

    US orders: 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Every order is tracked.

  • Questions? Ask us

    Write to contact@parispharmacy.com or use the chat.

Read our full story

Questions about this product? Chat with us

Payment and Security

  • Payment methods we accept
  • Amazon
  • American Express
  • Apple Pay
  • Bancontact
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • MB WAY
  • PayPal
  • Satispay
  • Shop Pay
  • USDC
  • Visa

Checkout is secured by Shopify over an encrypted connection, and your card details are never stored on this site. Returns are accepted within 30 days: read our shipping and returns page and our privacy policy.

La Roche-Posay Effaclar Duo+M Blemish Moisturizer
La Roche-Posay Effaclar Duo+M Blemish Moisturizer
Regular price $25.99

Free US shipping over $100*

Tracked, duties paid to the US. Arrives in 3 to 10 business days.

Large or heavy orders may carry a small additional charge, shown at checkout.

30 day easy returns

Return unopened products within 30 days. Damaged items replaced at no cost.

Authentic, direct from France

Real batch codes and original packaging, bought from French pharmacy brands.

As seen on Instagram

Paris Pharmacy on Instagram

Routines, unboxings and how to use, straight from our feed.

Play Reapply, every two hours
paris.pharmacy

Reapply, every two hours

Play Caudalie SPF 50 at the beach
paris.pharmacy

Caudalie SPF 50 at the beach

Play Caudalie Vinoperfect and the Instant Detox Mask
paris.pharmacy

Caudalie Vinoperfect and the Instant Detox Mask

Play Love these recs, find all these and more
paris.pharmacy

Love these recs, find all these and more

Play A French pharmacy haul, from A313 to Homeoplasmine
paris.pharmacy

A French pharmacy haul, from A313 to Homeoplasmine