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Bioderma Créaline Défensive Serum
Authentic French pharmacy formula
Sourced in Paris, shipped from California or Paris, in its original packaging.
Free US shipping over $100*
Tracked delivery on every order.
Delivered in 3 to 10 business days
Ships from California or Paris, tracked all the way to your door.
Returns within 30 days
Unopened products, returned by mail.
Your skin stings when you cleanse, flares red in cold weather, and reacts to everything. The Bioderma Crealine Defensive Serum rebuilds your barrier so you can finally tolerate the products you love. Three weeks in, your skin stops acting out.
Key Benefits
- Shields against daily aggressors: protects your barrier from pollution, temperature swings, and indoor heating
- Calms tightness and sting: soothes reactive, uncomfortable skin within the first application
- Hydrates without weight: squalane and glycerin replenish moisture while feeling invisible
- Reduces future flare-ups: strengthens your skin's defenses so reactions happen less often over time
- Supports your microbiome: Bioderma's ecobiology approach keeps good bacteria balanced
- Safe for hypersensitive types: hypoallergenic, fragrance-free, tested on reactive skin
Key Ingredients
Carnosine: a peptide that shields against free radicals and slows visible aging triggered by pollution and UV exposure. Hydrolyzed Hyaluronic Acid: a low-weight form that penetrates deeper to plump skin from within and hold moisture for hours. Squalane: a plant-based lipid that mimics your skin's natural oils, sealing in hydration without clogging pores. Salvia Miltiorrhiza Root Extract: a botanical active that soothes inflammation and calms redness. Palmitoyl Tetrapeptide-10: a peptide that strengthens the barrier by promoting collagen synthesis and ceramide production.
How to Use
Apply morning and evening after cleansing. Dispense three to four drops onto your fingertips. Press gently into your face and neck using light upward motions. Do not rub. Wait one minute, then follow with your moisturizer to lock in the actives. Barrier repair is progressive, so give this at least four weeks of daily use before evaluating results.
Ingredients
Key Ingredients
Carnosine: a peptide that shields against free radicals and slows visible aging triggered by pollution and UV exposure. Hydrolyzed Hyaluronic Acid: a low-weight form that penetrates deeper to plump skin from within and hold moisture for hours. Squalane: a plant-based lipid that mimics your skin's natural oils, sealing in hydration without clogging pores. Salvia Miltiorrhiza Root Extract: a botanical active that soothes inflammation and calms redness. Palmitoyl Tetrapeptide-10: a peptide that strengthens the barrier by promoting collagen synthesis and ceramide production.
Frequently Asked Questions
Can I use this with retinol or vitamin C?
How is this different from Crealine AR anti-redness serum?
Will this help rosacea-prone skin?
Does this feel heavy or greasy on oily skin?
Specifications
- SKU
- PP3701129805374
- Barcode
- 3701129805374
- Size
- 30ml
- Made in
- France
- Type
- Face Serum
- Brand
- Bioderma
Shipping and Returns
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Free US shipping over $100*
Tracked delivery in 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Orders below $100* ship at a flat rate shown at checkout.
Large or heavy orders may carry a small additional charge, shown at checkout. -
Duties paid to the US
US orders ship DDP: duties and taxes are paid upfront, nothing to pay at delivery. International orders may be subject to local duties and taxes on delivery, charged by the carrier.
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30 day returns
Unopened products in their original packaging, within 30 days of delivery. Email us and we send a prepaid return label.
Why Paris Pharmacy
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Authentic French pharmacy products
Sourced from French pharmacy suppliers, in their original packaging with batch codes.
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The French pharmacy brands
La Roche-Posay, Avene, Vichy, Bioderma, Caudalie, NUXE and more.
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Shipped from California or Paris
US orders: 3 to 5 business days from California or 5 to 10 business days from Paris, depending on the item. Every order is tracked.
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Questions? Ask us
Write to contact@parispharmacy.com or use the chat.
Questions about this product? Chat with us
Payment and Security
- Payment methods we accept
Checkout is secured by Shopify over an encrypted connection, and your card details are never stored on this site. Returns are accepted within 30 days: read our shipping and returns page and our privacy policy.
